Raw Feeding Veterinary Society

There is a dedicated team of veterinarians that advocate for the safe, responsible feeding of fresh, raw food for dogs and cats. These vets and other professionals are members of the Raw Feeding Veterinary Society (RFVS). Nicci is also a member of this organization as well and you can learn more about the RFVS here: https://rfvs.info/about-us/

Little Known fact, does your dog kiss your face?

Little Known Fact:

Do you let your pet kiss your face? We’re guilty! But we’ve heard some say this could be dangerous.

We were curious about where science stood on this behavior, so we consulted experts in both human and animal health to find out how bad it really is to let your pet kiss you on the mouth.

https://www.petnews.com.au/research/how-unsanitary-is-it-to-kiss-your-pet-on-the-mouth/

Cats Domesticated Themselves: Of course they did!

Though everyone might not agree on cats’ perfection, felines are among the most popular pets in the world today, with approximately 74 million cats living in U.S. homes.

The cat has long been important to human societies as a pest-control agent, object of symbolic value and companions. However, recent evidence from feline DNA shows they took their time domesticating themselves.

 

Article     |     Scientific Publication (Open Access)

Science of ‘Sense’ – how does your pet see the world?

There has always been debate about how and what dogs and cats can see. The reality? Dogs & cats don’t see as clearly as humans, and they’re lacking in the color department. However, they can see movement better than we can.

Learn Something New

One Health Initiative

One Health is an approach that recognizes that the health of people is closely connected to the health of animals and our shared environment. 

 

The World is changing, COVID has accelerated that change in countless ways. I believe that the unprecedented collaboration between disciplines and scientists from all over the world will be looked at as one of the most incredible feats in our modern world.  My hope is that this collaboration (and open access to scientific literature) continues and inspires other professionals to integrate their practices and their knowledge to work together to improve the lives of humans, animals and the environment. In fact, there is something called the One Health Initiative which aims to do just that.

So, what does this mean for us and our pets? What does it mean for nutrition? The reality is that there are numerous research gaps when it comes to nutrition, and even more when it comes to companion animal nutrition. The environment and how we interact with it also has a significant impact on the health of all living things. Much of the research we rely on for canine and feline supplementation, or management of disease is rooted in human research.

Many medical and nutrition professionals have recognized these significant gaps in human and animal medicine and nutrition. Livestock nutrition is arguably the most advanced of all nutrition sciences, followed by human nutrition, and it is frustrating to see the lack of knowledge sharing & collaboration between those and companion animal fields. This is a significant issue because it leaves treatment gaps for canines and felines such as cognitive dysfunction, allergies, gastrointestinal issues, diabetes, heart disease and more.

The One Health Initiative has provided individuals in many disciplines to collaborate and advance multiple fields of science to study and advance knowledge of zoonotic diseases, antimicrobial resistance, food safety and security and environmental factors. We look forward to providing updates and perspective on this initiative in the future.

The One Health Initiative provides opportunity for collaboration between veterinary and human physicians and researchers to advance both fields.

Source: https://onehealthinitiative.com/about/[vc_single_image image=”3888″ img_size=”600×427″ onclick=”custom_link” link=”https://onehealthinitiative.com/about/”]

The Big Miss: Is No-Hide® Actually Rawhide?

A ‘consumer advocate’ recently stirred up drama from July 2017 re-circulating an article (figure 1) claiming that Earth Animal No-Hide® treats were rawhide, again. This was on the heels of the announcement of a class-action lawsuit (figure 2) against Earth Animal Ventures (EAV) questioning the ingredients and sourcing of No-Hide® products. I didn’t think I would have to address this issue, but apparently, I do since misinformation and cherry-picked information from the original chain of events keeps circulating (if it’s on the internet it must be true, right?). Consumers and retailers alike need to see the situation for what it is, so I’ll also write this from both a retailer and consumer standpoint to provide the level of transparency I hold others to. As you read this, you’ll understand that both sides have significant issues. In fact, No-Hide® being (or not being) rawhide is hardly the issue. Instead there is a pervasive lack of transparency and misinformation from both the consumer advocate side and EAV.

Grain-Free Pet Food Diets | What to Know Before Switching

The benefit and necessity of grain-free pet food have come under scrutiny in recent years due to an FDA investigation due to a potential association with a canine heart disease known as dilated cardiomyopathy (DCM). As a result of this potential association, many have been told there is no scientific evidence to support the use of grain-free foods in canines and felines, or that these foods do not provide any benefit over grain-inclusive foods. For the most part, grain-free refers to kibble, although some have also categorized various canned, freeze-dried, and raw diets under the ‘grain-free’ umbrella. But are these claims accurate? Let’s find out:

 

Grain-free foods don’t provide benefits?grain free dog food kible

The pet food industry’s switch to grain-free was not fueled by a problem with the grains themselves or grain allergies like most believe. The largest pet food recalls in history was due to melamine and cyanuric acid contamination of ingredients coming from China. The short version of the 2007 recall is that wheat gluten and rice protein were intentionally combined with melamine for its high nitrogen content. Higher amounts of nitrogen can cause the protein content of an ingredient to test higher than it actually is. Since cyanuric acid was present, and the combination of melamine and cyanuric acid is likely the reason the recall was so deadly – not the melamine on its own. This series of events fueled the consumer trend of wanting grain-free pet food.

Other Concerns

Another major factor absent from the discussion on grain-free vs. grain inclusive diets for people – and pets – is the contamination of grains with herbicides, pesticides, mycotoxins, and fertilizers. This has become an increasingly large concern since the mid-’90s in both the human and animal food supply. Numerous peer-reviewed articles are detailing the disruption many of these agricultural contaminants have on normal gut bacteria function.1,2 In fact, available literature suggests that humans are becoming increasingly intolerant to grain and grain products for exactly these reasons (e.g. wheat & gluten sensitivity & celiac disease in humans).

We are learning that disruption of vital gut bacteria balance can have devastating effects on the health of the host, including diabetes, obesity, autoimmune disease, cancers, GI issues, and even DCM.3–5 Could the contamination of grains in pet food be one reason why many pets experience improvement of various issues with the change from grain-inclusive to grain-free? Could be.

Ultimately the phrase ‘there is no evidence to support the use of grain-free foods’ doesn’t mean there is not a benefit. It simply means that we have a major gap in research into companion animal nutrition and that we easily forget our recent history. On the contrary, we don’t have evidence to support that feeding grains to canines or felines are any more healthful than feeding grain-free diets. Evidence only shows that it meets minimal (known) nutritional standards, not that pets thrive on these processed diets. In short, canine and feline nutrition fields are far behind the knowledge we have in livestock and human nutrition.

 

Are ALL grain-free foods the same?

Many veterinarians and pet owners automatically lump grain-free cans, fresh food, raw food, and freeze-dried products as ‘grain-free’. While this is technically correct – there are stark differences that make these foods different from their kibble counterparts.

Regardless of whether we are feeding grain-free or not, we need to consider the high temps kibble and canned foods are heated to during the manufacturing process. This high heat creates Maillard Reaction Products (MRP) which is the name for a series of reactions that is the product of sugar (carbohydrate) and protein when heated. These are also known as AGE’s or Advanced Glycation End Products.

MRP’s are responsible for the nutrient loss and associated with diseases like diabetes, cardiovascular disease, kidney disease, loss of cognitive function, allergies, periodontal disease, and chronic inflammation.6–12 This can mean things like arthritis, skin, and ear issues, an old injury that keeps resurfacing, bloating, IBS, etc. Also, there is a large amount of research to suggest that they are carcinogenic and accelerate aging.13,14

  • Heterocyclic amines are MRPs from cooking protein that increases with elevated cooking temperature. This phenomenon is more pronounced in meat than fish – and these increase with temperature and dryness of meat or meat products15.
  • Acrylamides are a chemical that forms naturally from starchy foods during high-temperature cooking. According to the European Food Safety Authority evidence from animal studies shows that acrylamides are genotoxic and carcinogenic: they damage DNA and cause cancer. And since we know so little about animal nutrition is it possible that much of the disease we’re seeing – including DCM – has at least something to do with the MRP’s that are in dry and/or canned pet food? Is it a coincidence that freeze-dried, fresh, and raw options do not have as many associated issues as their processed counterparts? Maybe.

 

Allergic to Grains? Probably Not (sorry, not sorry)

Pet food can be made of everything from rendered unfit foods for human consumption to ingredients that are 100% organic and probably better than the food we feed ourselves. I’m not necessarily here to split hairs on ingredients and in the types of ingredients that are in our pet’s food. Because is it these ingredients that are causing the problem? Or is it something else? – These are the questions that the experts seem to avoid entirely. When a dog experiences issues related to food, we are quick as a society to turn over the bag and blame an ingredient or set of ingredients. However, those ingredients as listed are likely not the problem – rather the quality, processing agents, AGE’s and contamination of these ingredients (e.g. herbicides, pesticides, etc.); something you will never find listed on a label.

 

More Important: Nutrient Availability & Digestibility

The digestibility of food is altered as it is processed, mixed with other ingredients, and heated. That said, canned and kibble foods by definition will have varying levels of nutrient availability and digestibility than their lesser processed counterparts. The ingredients (or set of ingredients) that make up a food could be the most nutrient-dense food available – but if they are not digestible by the cat or dog then those ingredients are irrelevant. In short, this means that it is important to ask your pet food company for their digestibility and nutrient analysis to determine if their food is adequate for your pet. Learn more about what questions to ask and why here.

 

About the author: Nicole Cammack

Nicci is the owner of award-winning NorthPoint Pets & Company, in Connecticut. She is also the Founder & CEO of Undogmatic Inc. Her undergraduate and graduate education includes biology, chemistry, business, and nutrition. She has worked in the pharmaceutical industry on multiple R&D projects and has had the privilege to learn from leading international figures in the human and pet health industry. She regularly lectures at national conferences, including federal, state, and municipal K9 events. Her current research involves identifying pathogenic risk factors and transmission among raw fed pets through a comprehensive worldwide survey.

www.northpointpets.com

www.undogmaticinc.com

 

References:

  1. Van Bruggen AHC, He MM, Shin K, et al. Environmental and health effects of the herbicide glyphosate. Sci Total Environ. 2018;616-617:255-268. doi:10.1016/j.scitotenv.2017.10.309
  2. Aitbali Y, Ba-M’hamed S, Elhidar N, Nafis A, Soraa N, Bennis M. Glyphosate based- herbicide exposure affects gut microbiota, anxiety and depression-like behaviors in mice. Neurotoxicol Teratol. 2018;67:44-49. doi:10.1016/j.ntt.2018.04.002
  3. DeGruttola AK, Low D, Mizoguchi A, Mizoguchi E. Current Understanding of Dysbiosis in Disease in Human and Animal Models. Inflamm Bowel Dis. 2016;22(5):1137-1150. doi:10.1097/MIB.0000000000000750
  4. Galland L. The Gut Microbiome and the Brain. J Med Food. 2014;17(12):1261-1272. doi:10.1089/jmf.2014.7000
  5. Yoshida N, Yamashita T, Hirata K. Gut Microbiome and Cardiovascular Diseases. Diseases. 2018;6(3). doi:10.3390/diseases6030056
  6. Jandeleit-Dahm K, Cooper ME. The Role of AGEs in Cardiovascular Disease. doi:info:doi/10.2174/138161208784139684
  7. Pion PD, Kittleson MD, Thomas WP, Skiles ML, Rogers QR. Clinical findings in cats with dilated cardiomyopathy and relationship of findings to taurine deficiency. J Am Vet Med Assoc. 1992;201(2):267-274.
  8. DCM: add taurine to grain-free dog foods, say scientists. Accessed May 15, 2019. https://www.petfoodindustry.com/articles/8162-dcm-add-taurine-to-grain-free-dog-foods-say-scientists?v=preview
  9. DACVIM CDSBM. Breed-specific variations of cardiomyopathy in dogs. dvm360.com. Accessed May 15, 2019. https://veterinarynews.dvm360.com/breed-specific-variations-cardiomyopathy-dogs
  10. Dilated Cardiomyopathy in Dogs. vca_corporate. Accessed May 15, 2019. vcahospitals.com/know-your-pet/dilated-cardiomyopathy-dcm-in-dogs–indepth
  11. Medicine C for V. FDA Investigation into Potential Link between Certain Diets and Canine Dilated Cardiomyopathy. FDA. Published online June 27, 2019. Accessed June 29, 2019. https://www.fda.gov/animal-veterinary/news-events/fda-investigation-potential-link-between-certain-diets-and-canine-dilated-cardiomyopathy
  12. Freeman LM, Stern JA, Fries R, Adin DB, Rush JE. Diet-associated dilated cardiomyopathy in dogs: what do we know? J Am Vet Med Assoc. 2018;253(11):1390-1394. doi:10.2460/javma.253.11.1390
  13. Prasad C, Imrhan V, Marotta F, Juma S, Vijayagopal P. Lifestyle and Advanced Glycation End Products (AGEs) Burden: Its Relevance to Healthy Aging. Aging Dis. 2014;5(3):212-217. doi:10.14336/AD.2014.0500212
  14. Turner DP. Advanced glycation end-products: a biological consequence of lifestyle contributing to cancer disparity. Cancer Res. 2015;75(10):1925-1929. doi:10.1158/0008-5472.CAN-15-0169
  15. Jägerstad M, Skog K, Arvidsson P, Solyakov A. Chemistry, formation and occurrence of genotoxic heterocyclic amines identified in model systems and cooked foods. Z Für Leb -Forsch A. 1998;207(6):419-427. doi:10.1007/s002170050355

Hemp & CBD: Not All CBD is “Natural”

In part II we discussed phytoremediation, and why this is one of the largest hidden risks for those who give CBD to their pets or consume it themselves. To review, cannabis absorbs heavy metals, and many of the agricultural chemicals in the soil such as pesticides, herbicides, and fertilizers. If a company does not have processes and procedures in place that ensure their product is free from contaminants and is actually the concentration that is listed on the label. Don’t believe this is a real issue? Due to a lack of regulation, hemp products have the potential for significant risks.

Consequences Due to Lack of Regulationrisks of hemp products

Unfortunately, due to the phytoremediation properties of hemp, contaminants and formulation errors are common and often go unnoticed. For example, a recent study by Cornell University showed 10 out of 29 CBD products tested were within 10% of the concentration on the label.  That same study also showed that heavy metal contaminants were found in 4 out of 29 products.19 Stop and read that again – because it means that only 34% of the most popular CBD’s were even the correct concentration. Never mind those with contamination issues…Yikes!

Spoiler alert: these are some of the most popular pet CBD supplements on the market today. Most of them are sold locally to Cheshire – so you may want to pay attention.

Lack of regulation for CBD means that companies who are NOT members of the NASC are not required to test raw ingredients or finished products for contaminants or adequacy. Heavy metal contamination, poor sourcing, and/or formulation errors could potentially be a contributing factor to elevated liver function testing and other documented adverse effects relating to hemp & CBD use. This highlights the need to screen companies for adequate product testing and transparency. The reality is that a very small handful of companies can provide verification that their products are contaminant-free, or within concentrations listed on the label.

Ask Questions Verifying Quality

When looking for a CBD product, or any supplement for yourself or your pets you must ask the following questions:

  • Are you a member of the NASC? (pets only)
  • Do you inbound test your raw and concentrated ingredients for contaminants such as heavy metals, fertilizers, and other agricultural chemicals?
  • Do you test your raw ingredients specifically active ingredients to ensure their concentrations are correct?
  • Do you source any ingredients from China?
    • Are you willing to provide certificates of origin?
    • Note that ingredients from China are not necessarily bad if they are responsibly sourced, and they are verifying quality and purity.
  • Do you complete an analysis of your final product to ensure the formulation is correct and ensure there are not any contamination issues? This is important to ensure that active ingredients match the label.

If companies are unwilling to transparently ask these questions or use the excuse of information being proprietary, I would strongly suggest that you find another brand. Not being transparent or testing products when it comes to ensuring safety is unacceptable. Brands that are not meeting these standards could potentially be poisoning the market for other companies who do their due diligence. As consumers, demand better.

Summary

CBD may have its benefits when well-sourced and formulated. While more research is needed, this is a common problem for a lot of supplements and pharmaceuticals on the market. Overall, the risk of adverse effects appears to be low, but consideration should be taken for those pets who may have liver problems.

Some veterinarians are well educated in the CBD landscape and available products, and some simply are not. If your vet is unable to provide information or recommend products it is ok to ask them for someone who can. Many reputable companies do have veterinarians and scientists on-staff that you or your veterinarian may also be able to speak to for more information.

As always, this is a rapidly evolving field. We expect to see changes as the FDA and AVMA begin to release more guidance and information in this area. We also will see more research regarding safety, efficacy, and other applications as time goes on. While it can be frustrating to see both advice and information change, remember this is a good thing and something you should embrace and support!

Did you miss part I, II, III of this series?

About the Author: Nicole Cammack

Nicci is the owner of award-winning NorthPoint Pets & Company, in Connecticut. She is also the Founder & CEO of Undogmatic Inc. Her undergraduate and graduate education includes biology, chemistry, business, and nutrition. She has worked in the pharmaceutical industry on multiple R&D projects and has had the privilege to learn from leading international figures in the human and pet health industry. She regularly lectures at national conferences, including federal, state, and municipal K9 events. Her current research involves identifying pathogenic risk factors and transmission among raw fed pets through a comprehensive worldwide survey.

www.northpointpets.com

www.undogmaticinc.com

References

  1. Sawler J, Stout JM, Gardner KM, et al. The Genetic Structure of Marijuana and Hemp. PLoS ONE. 2015;10(8). doi:10.1371/journal.pone.0133292
  2. Marijuana, the Second Trip. Revised Edition by Bloomquist, Edward R.: Good PAPERBACK | Earthlight Books. Accessed June 3, 2020. https://www.abebooks.com/Marijuana-Second-Trip-Revised-Edition-Bloomquist/22676164305/bd
  3. Kogan L, Schoenfeld-Tacher R, Hellyer P, Rishniw M. US Veterinarians’ Knowledge, Experience, and Perception Regarding the Use of Cannabidiol for Canine Medical Conditions. Front Vet Sci. 2019;5. doi:10.3389/fvets.2018.00338
  4. Fitzgerald KT, Bronstein AC, Newquist KL. Marijuana Poisoning. Top Companion Anim Med. 2013;28(1):8-12. doi:10.1053/j.tcam.2013.03.004
  5. Mackie K. Cannabinoid Receptors: Where They are and What They do. J Neuroendocrinol. 2008;20(s1):10-14. doi:10.1111/j.1365-2826.2008.01671.x
  6. Maroon J, Bost J. Review of the neurological benefits of phytocannabinoids. Surg Neurol Int. 2018;9. doi:10.4103/sni.sni_45_18
  7. Levinsohn EA, Hill KP. Clinical uses of cannabis and cannabinoids in the United States. J Neurol Sci. 2020;411:116717. doi:10.1016/j.jns.2020.116717
  8. Mechanisms of CB1 receptor signaling: endocannabinoid modulation of synaptic strength | International Journal of Obesity. Accessed June 5, 2020. https://www.nature.com/articles/0803273
  9. Commissioner O of the. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD). FDA. Published online March 10, 2020. Accessed June 4, 2020. https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  10. Commissioner O of the. FDA Warns Companies Illegally Selling CBD Products to Treat Medical Conditions, Opioid Addiction. FDA. Published April 26, 2020. Accessed June 6, 2020. https://www.fda.gov/news-events/press-announcements/fda-warns-companies-illegally-selling-cbd-products-treat-medical-conditions-opioid-addiction
  11. How CBD pet product brands avoid federal warnings. Accessed June 12, 2020. https://www.petfoodindustry.com/articles/8793-how-cbd-pet-product-brands-avoid-federal-warnings
  12. Drug Scheduling. Accessed June 6, 2020. https://www.dea.gov/drug-scheduling
  13. AVMA weighs in at cannabis hearing. American Veterinary Medical Association. Accessed June 17, 2020. https://www.avma.org/javma-news/2019-08-15/avma-weighs-cannabis-hearing
  14. FAQs. NASC LIVE. Accessed June 13, 2020. https://nasc.cc/faqs/
  15. Resnik DB. Beyond post-marketing research and MedWatch: Long-term studies of drug risks. Drug Des Devel Ther. 2007;1:1-5.
  16. Deabold KA, Schwark WS, Wolf L, Wakshlag JJ. Single-Dose Pharmacokinetics and Preliminary Safety Assessment with Use of CBD-Rich Hemp Nutraceutical in Healthy Dogs and Cats. Animals. 2019;9(10):832. doi:10.3390/ani9100832
  17. McGrath S, Bartner LR, Rao S, Kogan LR, Hellyer PW. A Report of Adverse Effects Associated With the Administration of Cannabidiol in Healthy Dogs. :5.
  18. Commissioner O of the. What You Need to Know (And What We’re Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD. FDA. Published online March 3, 2020. Accessed June 12, 2020. https://www.fda.gov/consumers/consumer-updates/what-you-need-know-and-what-were-working-find-out-about-products-containing-cannabis-or-cannabis
  19. Wakshlag JJ, Cital S, Eaton SJ, Prussin R, Hudalla C. Cannabinoid, Terpene, and Heavy Metal Analysis of 29 Over-the-Counter Commercial Veterinary Hemp Supplements. Vet Med Res Rep. 2020;11:45-55. doi:10.2147/VMRR.S248712

CBD & Hemp: Hemp, CBD (and other) Safety Considerations

In part I and part II we discussed the history of CBD, how it works, and the legality behind CBD for pets & people. While this can all seem a little overwhelming, especially considering the wide availability of CBD – the main take away is that it is important to be safe when choosing any supplement. One of the reasons I decided to put together such a robust series was to explain why it was so important to look for quality and transparency in products. I can tell you all day that quality and transparency are important, but if I don’t explain the reasoning, it just becomes a hollow message.

Part III dives into the clinical data available for CBD use in pets. We’ll also look at what to do if your pet ingests marijuana. Unfortunately, this is a common incident, and THC within marijuana products is an emergency. Finally, we’ll discuss why there is not more available data on dosing, and just why this may be different for each pet.

Hemp & Marijuana: Available Data, Risks & Clinical Information

No established long-term safety data for Hemp/CBD in pets, however, this is not unlike many pharmaceutical medications and supplements already on the market.15 Recent short term data from a recent small study of cats and dogs given 2mg of CBD twice daily for 12 weeks determined that CBD was not detrimental to complete blood counts (CBC) or biochemistry values. It was determined that CBD in cats is metabolized differently than dogs, and needs further evaluation to determine appropriate dosing.4 Additionally, one cat experienced rising levels of ALT, a liver enzyme, which also requires further investigation.16 Additional studies have shown an elevation in ALP, another liver enzyme, further identifying the need for more research.17 This is in line with findings on the human side regarding use of CBD.18

Marijuana itself does have well-documented risks for pets that stem from THC. Even though this is not used or recommended for pets, exposure is common through the ingestion of their owner’s marijuana supply. The minimum lethal oral dose for dogs for THC is more than 3 g/kg, and has been seen most commonly with the ingestion of THC butter.4 Treatment of THC/marijuana ingestion in animals is largely supportive. Meaning that no specific antidote presently exists for THC poisoning. The majority of dogs experiencing intoxication after marijuana ingestion recover completely without long term effects or deficit.4

Clinical effects of toxic levels of THC/marijuana ingestion are generally seen within 60 minutes. Signs of canine intoxication include depression, hyper-salivation, mydriasis, hypermetria, vomiting, urinary incontinence, tremors, hypothermia, and bradycardia. Higher dosages may additionally cause nystagmus, agitation, tachypnea, tachycardia, ataxia, hyper-excitability, and seizures.4 If you suspect your pet has ingested marijuana seek immediate veterinary care.

Toxin Concerns: Phytoremediation

In our last article, we discussed the lack of accountability and product adequacy testing within the human and pet supplement market. When it comes to toxic screening, cannabis in all form are of concern, because it can be a highly toxic plant. This is because it performs a process called phytoremediation and therefore adds another level of concern to the equation. Phytoremediation means that cannabis absorbs heavy metals and many of the agricultural chemicals in the soil such as pesticides, herbicides, and fertilizers. Many CBD companies like to hide behind the word ‘proprietary’ when it comes to analysis or ingredient sourcing. However, this is not an excuse that holds any weight when it comes to the safety of cannabis, period. Fortunately, the National Animal Supplement Council (NASC) works with some CBD companies to help protect against contaminated CBD products and other supplements from entry to the marketplace. In other words, it is wise to avoid pet supplements without the NASC seal. We discussed the NASC in more detail in Article II.

Dosing for CBD Products

A variety of CBD containing products are on the market for people and pets. These include oral oils, pills, capsules & food products like treats and honey.  There are also balms and other transdermal-type products that are designed for use on skin. Products have varying levels of effectiveness that likely have to do with quality, purity, concentration, and dosage. Exact dosing of CBD dosing for pets is still being established and is largely up for debate. Further complicating this issue is that some hypothesize this could be highly individualized.

Fortunately, CBD containing hemp products, by law, are to have 0.3% THC or less on a dry weight basis, so the risk of overdose from THC is quite low.9 This does not however mean that dosing CBD, hemp products in pets should not be measured or monitored. Always follow veterinarian and/or product label instructions.

Summary

We’ve all heard the claims of benefits for CBD for both pets and people, however, we now know that those claims are largely unsupported by science and that companies are likely in violation when making these claims. Regarding safety, it appears that there are few adverse events. For CBD have been reported, however, some studies point to a potential for concerns for liver values. This area needs further research, and we’re sure that more data will be available in the near future. If your pet has had or currently has any liver concerns, it is important to discuss CBD use with your veterinarian prior to using it. In addition, if you decide to use CBD it is paramount to ensure the product is NASC compliant. There are also several questions that you can ask your CBD (or any supplement company) which we will discuss in Part IV! Did you miss part I and part II of the CBD & Hemp series?

About the Author: Nicole Cammack

Nicci is the owner of award-winning NorthPoint Pets & Company, in Connecticut. She is also the Founder & CEO of Undogmatic Inc. Her undergraduate and graduate education includes biology, chemistry, business, and nutrition. She has worked in the pharmaceutical industry on multiple R&D projects and has had the privilege to learn from leading international figures in the human and pet health industry. She regularly lectures at national conferences, including federal, state, and municipal K9 events. Her current research involves identifying pathogenic risk factors and transmission among raw fed pets through a comprehensive worldwide survey.

www.northpointpets.com
www.undogmaticinc.com

References
  1. Sawler J, Stout JM, Gardner KM, et al. The Genetic Structure of Marijuana and Hemp. PLoS ONE. 2015;10(8). doi:10.1371/journal.pone.0133292
  2. Marijuana, the Second Trip. Revised Edition by Bloomquist, Edward R.: Good PAPERBACK | Earthlight Books. Accessed June 3, 2020. https://www.abebooks.com/Marijuana-Second-Trip-Revised-Edition-Bloomquist/22676164305/bd
  3. Kogan L, Schoenfeld-Tacher R, Hellyer P, Rishniw M. US Veterinarians’ Knowledge, Experience, and Perception Regarding the Use of Cannabidiol for Canine Medical Conditions. Front Vet Sci. 2019;5. doi:10.3389/fvets.2018.00338
  4. Fitzgerald KT, Bronstein AC, Newquist KL. Marijuana Poisoning. Top Companion Anim Med. 2013;28(1):8-12. doi:10.1053/j.tcam.2013.03.004
  5. Mackie K. Cannabinoid Receptors: Where They are and What They do. J Neuroendocrinol. 2008;20(s1):10-14. doi:10.1111/j.1365-2826.2008.01671.x
  6. Maroon J, Bost J. Review of the neurological benefits of phytocannabinoids. Surg Neurol Int. 2018;9. doi:10.4103/sni.sni_45_18
  7. Levinsohn EA, Hill KP. Clinical uses of cannabis and cannabinoids in the United States. J Neurol Sci. 2020;411:116717. doi:10.1016/j.jns.2020.116717
  8. Mechanisms of CB1 receptor signaling: endocannabinoid modulation of synaptic strength | International Journal of Obesity. Accessed June 5, 2020. https://www.nature.com/articles/0803273
  9. Commissioner O of the. FDA Regulation of Cannabis and Cannabis-Derived Products, Including Cannabidiol (CBD). FDA. Published online March 10, 2020. Accessed June 4, 2020. https://www.fda.gov/news-events/public-health-focus/fda-regulation-cannabis-and-cannabis-derived-products-including-cannabidiol-cbd
  10. Commissioner O of the. FDA Warns Companies Illegally Selling CBD Products to Treat Medical Conditions, Opioid Addiction. FDA. Published April 26, 2020. Accessed June 6, 2020. https://www.fda.gov/news-events/press-announcements/fda-warns-companies-illegally-selling-cbd-products-treat-medical-conditions-opioid-addiction
  11. How CBD pet product brands avoid federal warnings. Accessed June 12, 2020. https://www.petfoodindustry.com/articles/8793-how-cbd-pet-product-brands-avoid-federal-warnings
  12. Drug Scheduling. Accessed June 6, 2020. https://www.dea.gov/drug-scheduling
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